Thesis Esther de Boer
On 13 November 2025 (10:00 AM), Esther de Boer expects to defend her PhD thesis 'Curbing the cascade: activation and regulation of the complement system on red blood cells' at the University of Amsterdam.
Promotor: Prof TW Kuijpers MD PhD
Copromotores: I Jongerius PhD and RB Pouw PhD
Venue: Agnietenkapel, University of Amsterdam
Abstract (to follow)
Chapters
Chapter 1
General introduction
Chapter 2
The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation abstract
Chapter 3
The distribution of complement regulators during in vivo and in vitro erythropoiesis
Chapter 4
A pedigree with CHAPLE disease: variable penetrance and treatment with pozelimab abstract
Chapter 5
Cell-free COSS is secreted into circulation in PNH patients
Chapter 6
Cl-inhibitor treatment in patients with severe complement mediated autoimmune hemolytic anemia abstract
Chapter 7
A novel flow cytometry-based indirect antiglobulin test (Flow IAT) reveals hidden lgM as driver of complement activation in cold and warm autoimmune hemolytic anemia
Chapter 8
Vesiculation as potential novel pathogenic mechanism in lgA autoimmune hemolytic anemia (AIHA) abstract
Chapter 9
General discussion
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