Thesis Saskia van der Velden

On 5 September 2025 (1:00 PM) Sanquin researcher Saskia van der Velden expects to defend her PhD thesis "TRALI pathophysiology: Tipping the balance" at the University of Amsterdam.

Promotor: Prof CE van der Schoot MD PhD
Copromotor: R Kapur PhD

Venue: Agnietenkapel, University of Amsterdam

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Abstract

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Chapters

Chapter 1

Introduction

Chapter 2

Evaluation of platelet responses in transfusion-relateo acute lung injury (TRALI) abstract
 

Chapter 3

Update on the pathophysiology of transfusion-related acute lung injury abstract
 

Chapter 4

Biological and structural characterization of murine TRALI antibody reveals increased Fe-mediated complement activation abstract
 

Chapter 5

Complement activation drives Transfusion-related acute lung injury via "Tiacrophage" trafficking and formation of NETs abstract
 

Chapter 6

Early low pulmonary alveolar macrophage and eosinophil levels characterize antibody-mediated transfusion-related acute lung injury

Chapter 7

Pancreatic involvement in murine antibody-mediated transfusion-related acute lung injury? abstract
 

Chapter 8

General discussion
 

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