Thesis Stijn Groten

On 4 September 2025 (10:15 AM) Sanquin researcher Stijn Groten expects to defend his thesis ‘Proteomic perspectives on Endothelial Responses’ at Utrecht University.

Promotor: Prof AB Meijer PhD 

Copromotores: M van den Biggelaar PhD, Arjen Hoogendijk PhD

Venue: Utrecht University, Academy Building

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Abstract

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Chapters

Chapter 1

General introduction

Chapter 2

The proteomic landscape of in vitro cultured endothelial cells across vascular beds abstract

Chapter 3

Multi-omics delineation of cytokine-induced endothelial inflammatory states abstract

Chapter 4

Inhibiting synergetic endothelial inflammation through targeting NFKB and JAK/STAT

Chapter 5

Integrative phosphoproteomic analysis reveals hemostatic-endothelial signaling interplay abstract

Chapter 6

Von Willebrand disease specific defects and proteomic signatures in endothelial colony forming cells abstract

Chapter 7

Impaired secretion of Von Willebrand Factor in patients with biallelic mutations in the guanine nucleotide exchange factor MADD

 Chapter 8

Discussion

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