Thesis Eduard Ebberink

On 11 December 2017 (10:30 hrs) Eduard Ebberink defended his thesis 'Footprinting haemostatic networks' at Utrecht University.

Promotores: Prof K Mertens PhD and prof AB Meijer PhD
Venue: Academiegebouw, Utrecht University

Chapters

Chapter 1
Introduction

Chapter 2
A novel chemical foot printing approach identifies critical lysine 23 residues involved in the binding of receptor-associated-protein to cluster II of LDL receptor-related protein. Abstract

Chapter 3
Factor Vlll/V C-domain swaps reveal discrete C-domain roles in 47 factor VIII function and intracellular trafficking. Abstract

Chapter 4
Role of glycine in catalytic activity of Hyaluronan-Binding Protein 2. Abstract

Chapter 5
Probing activation-driven changes in coagulation factor X, IX and prothrombin by primary amine labeling.

Chapter 6
The 220-loop in coagulation factor IX revisited: role of basic and acidic residues in the catalytic activity

Chapter 7
Summarizing discussion