Thesis Twan de Waard
On 19 May 2021 Sanquin researcher Twan de Waard defended his thesis 'Tuning the Show: Genetic engineering to unravel antigen presentation by the Human Leukocyte Antigen class I'.
Promotor: Prof SM van Ham PhD
Copromotor: RM Spaapen PhD
Venue: Agnietenkapel, University of Amsterdam and online
Chapters
Chapter 1
General introduction and scope of this thesis
Chapter 2
PAKC: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin Abstract
Chapter 3
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens Abstract
Chapter 4
HLA-I allelic dependencies on components of the peptide-loading complex
Chapter 5
The role of glycosphingolipids in immune cell functions Abstract
Chapter 6
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses Abstract
Chapter 7
Summarizing discussion
Download
Download PhD thesis (university repository)