Guest speaker Maike Hansen | Noise control: Do cells tune gene expression fluctuations to impact cell fate decisions?
Medical priority Immunotherapy
| Date | 2 December 2025 |
|---|---|
| Location | Auditorium Sanquin Plesmanlaan 125 1066 CX Amsterdam The Netherlands |
| Time | 13:00 to 14:00 |
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Tuesday 2 December Maike Hansen PhD (Institute for Molecules and Materials Biophysical Chemistry, Radboud University, Nijmegen, The Netherlands) will give a guest lecture at Sanquin Amsterdam.
Host: Monika Wolkers,
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Although often seen as a hindrance, gene expression noise can promote cellular diversification in both healthy and diseased contexts. Here, we show how noise drives fate transitions in mouse embryonic stem cells and identify SON, a protein involved in nuclear speckle formation, as a noise regulator whose effects shape cell fate decisions.