Marieke von Lindern PhD
Research group Hematopoies
Department of Hematopoiesis
Hematopoiesis is the process by which mature peripheral blood cells are formed from the hematopoietic stem cell (HSC). This process involves maintenance of the stem cell compartment, commitment of multipotent progenitors into the various lineages of the blood cell system, transient amplification of progenitor pools, and maturation to functional cells that are released into the circulation.
Sanquin is dedicated to develop and supply novel cellular products adapted to the future perspective of personalized medicine.
The Department of Hematopoiesis aims to be an expertise centre for basic research on survival, maintenance and lineage commitment of hematopoietic stem- and progenitor cells, and on the maturation of progenitors into functional peripheral blood cells. Whenever possible, we will use this knowledge for the development of novel cellular products that could be produced by the stem cell laboratory.
|Bone marrow microenvironment (group leader: Carlijn Voermans)||T cell differentiation (group leader: Monika Wolkers)|
|Erythropoiesis (group leader: Emile van den Akker)||mRNA translation in erythropoiesis (group leader: Marieke von Lindern)|
|Megakaryocytopoiesis (group leader: Daphne Thijssen-Timmer)|
|Marieke von Lindern|
|Department of Hematopoiesis|