Thesis Huan Zhang
On 3 September 2026 (1:00 PM) Huan Zhang expects to defend his PhD thesis 'From Development to Disease: cellular models of hematopoiesis and platelet disorders' at the Erasmus University Rotterdam
Promotor: Prof JNJ Philipsen PhD
Co-promotor: E van den Akker PhD
Venue: Senaats zaal, Erasmus Building, Woudestein Campus, Rotterdam
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Chapters
Chapter 1
Introduction
Chapter 2
Generation and characterization of human iPSC line SANiOll- A from a patiënt with an inherited platelet disorder carrying the heterozygous FLI1 c.297del variant abstract
Chapter 3
Generation and characterization of human iPSC line SANiO12- A from a patiënt with an inherited platelet disorder carrying the heterozygous ETV6 c.llO5C>T variant abstract
Chapter 4
LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in iPSC-derived hemogenic endothelium abstract
Chapter 5
Heterozygous nonsense FLI1 p.MetlOO* variant results in thrombocytopenia and increased erythroid gene expression abstract
Chapter 6
ETV6/TEL knockout leads to impaired megakaryocytic gene regulation, which is phenocopied by the ETS-domain variant ETV6 p.R369W via dominant-negative actions
Chapter 7
General discussion
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Download PhD thesis from university repository (when available)