Thesis Suzanne Gunnink

On 31 January 2020 Suzanne Gunnink defended her thesis 'Not all that glitters is gold – platelet transfusions for preterm neonates'

She received her PhD cum laude.

Promotores: Prof CJ Fijnvandraat MD PhD and Prof E Lopriore MD PhD
Copromotores: Prof JG van der Bom MD PhD and SJ Stanworth MD PhD
Venue: Agnietenkapel, University of Amsterdam

Chapters

Chapter 1
General introduction and outline of the thesis

PART I. WHAT DO WE KNOW ABOUT THROMBOCYTOPENIA, TRANSFUSIONS AND BLEEDING IN NEONATES?


Chapter 2 
Neonatal thrombocytopenia: etiology, management and outcome. 
Expert Review of Hematology 2014;7(3):387-95.

Chapter 3 
Are thrombocytopenia and platelet transfusions associated with major bleeding in preterm neonates? A systematic review. 
Blood Reviews 2019;36:1-9

Chapter 4 
Early-Onset Thrombocytopenia in Small-For-Gestational-Age Neonates: A Retrospective Cohort Study. 
PLoS One 2016 May 13;11(5):e 0154853.

PART II. DO PLATELET TRANSFUSIONS WORK?


Chapter 5
A randomized trial of neonatal platelet transfusion thresholds.
New England Journal of Medicine 2019;380(3):242-251.

Chapter 6 
Preterm neonates benefit from low prophylactic platelet transfusion threshold despite varying risk of bleeding or death. 
Revised version published in: Blood 2019 Oct 24. Epub ahead of print.

Chapter 7 
Do platelet transfusions reduce bleeding risk in preterm neonates with severe thrombocytopenia? A time-dependent propensity score matched cohort analysis.

PART III. CAN WE PREDICT MAJOR BLEEDING IN NEONATES?


Chapter 8

Dynamic prediction of bleeding risk in thrombocytopenic preterm neonates.
Haematologica 2019 Nov;104(11):2300-2306

PART IV. DISCUSSION AND FUTURE PERSPECTIVES


Chapter 9
Platelet and red cell transfusions for neonates: lifesavers or trojan horses? 
Revised version published in: Exp Rev Haem 2019 Oct; 12(10):797-800.

Download

Download PhD thesis (university repository)