Thesis Christine Bruggeman
On 22 March 2019 Christine Bruggeman defended her PhD thesis 'Expression and function of Fc-gamma receptors; Binding of Immunoglobulin G and its glycoforms' at the University of Amsterdam.
Promotor: Prof Taco Kuijpers MD PhD
Copromotor: Prof Timo van den Berg PhD
Venue: Agnietenkapel, University of Amsterdam
Chapters
Chapter 1
General introduction
Chapter 2
Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-γ receptors. Abstract
Chapter 3
Tissue-specific expression of IgG receptors by human macropages ex vivo
Chapter 4
ABO zygosity, but not secretor or Fc receptor status, is a significant risk factor for IVIG-associated hemolysis. Abstract
Chapter 5
Increasing incidence of treatment-associated hemolysis in Kawasaki Disease: association with blood-group antibody titers in IVIG products
Chapter 6
Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile. Abstract
Chapter 7
IgG Glyco-Engineering to Improve IVIg Potency. Abstract
Chapter 8
General discussion
