Blood Cell Research
The department of Blood Cell Research harbors the Phagocyte Laboratory and the Laboratory for Blood Transfusion Technology.
In the Phagocyte Laboratory, three major blood cell types are investigated: erythrocytes, platelets and neutrophilic granulocytes. The first two cell types are regular transfusion products used for patients. The latter might become one. The three blood cell types play an essential role in, respectively, oxygen transport, blood clotting and in innate immunity, the inborn immune system against invading micro-organisms.
The aim of our research is to understand important metabolic processes in these cells. In this way we can better maintain the quality of these cells after donation and develop new diagnostic tools in order to identify aberrations in patients.
In our research we use a variety of biochemical, immunological and microscopic techniques. In addition, nucleic acid research and flow cytometry are used in the ongoing projects.
Laboratory for Blood Transfusion Technology
The laboratory for Blood Transfusion Technology performs applied research to increase the knowledge of current and future blood products as well as materials. New devices and materials are evaluated, and methods to evaluate the quality of blood products are developed and/or improved. Special attention is given to the link between in vitro and in vivo evaluation through cooperation with the department of Transfusion Medicine. The Principal Investigator is also senior scientist in the phagocyte laboratory of the department of Blood Cell Research, and is involved in more fundamental projects on erythrocytes and platelets. In this way the Blood Bank has early access to results obtained in the Research division for product development and improvement.
|Erythrocytes (group leader: Robin van Bruggen)||Bacterial safety of blood products (group leader: Dirk de Korte)|
|Platelets (group leader: Laura Guiterrez)||In vitro quality tests for cellular blood products (group leader: Dirk de Korte)|
|Improving materials and methods for storage of blood components (group leader: Dirk de Korte)|
Project leader: Johan Lagerberg PhD
Projects for an internship for students in biomedical sciences (University or HLO) are generally available and ideas for projects are welcome to be discussed. For more information and an overview of the current internships visit the student projects page.