Sanquin’s collaborations in regenerative & immuno therapy:
The department of Hematology of the AMC obtains (stem) cell products from the Laboratory for Cell Therapy for patient care. Furthermore the LCT participates in HOVON studies that are carried out in the AMC.
Emma Children’s Hospital-AMC
The department of Hematology of the Emma Children’s Hospital obtains (stem) cell products from the Laboratory for Cell Therapy for patient care.
The department Medical Oncology of the AvL obtains (stem) cell products from the Laboratory for Cell Therapy for patient care.
Within the department of Immunology of the Netherlands Cancer Institutes several trials on T-cell Immunotherapy are conducted by the group of Prof Ton Schumacher together with Dr. John Haanen from the AvL.
The Laboratory for Cell Therapy of Sanquin is involved in the generation of TIL and cryopreservation and quality control assays on T-cells for these trials.
Radboud University Nijmegen
The department of Tumor Immunology, headed by Carl Figdor, performs clinical trials in which cancer patients are vaccinated with dendritic cells (DCs).
The department of Immunopathology and the Laboratory for Cell Therapy of Sanquin collaborate with the group of Carl Figdor on the production and optimization of DC vaccines.
In this validation project, funded by the LSCA, Sanquin and DCPrime will combine their expertise and validate whether Sanquin’s patented technology on DC maturation & migration (WO2007078196) is applicable to off-the-shelf DCs from DCPrime to optimally exploit their technology platforms.
Within the department of Immunohematology and Blood Transfusion of the LUMC clinical trials are conducted with mesenchymal stromal cells (MSCs) to treat various types of diseases. The Laboratory for Cell Therapy of Sanquin produces MSCs for the treatment of patients suffering from steroid-resistant Graft versus Host Disease.