Guest lecture Bassem Mohammed
Medical priority Bleeding and Hemostasis
| Date | 10 July 2026 |
|---|---|
| Location | Auditorium Sanquin Plesmanlaan 125 1066 CX Amsterdam The Netherlands |
| Time | 13:00 to 14:00 |
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Tuesday 10 July 2026 Bassem Mohammed PhD, Saint Louis University School of Medicine, St. Louis, USA, will give a guest lecture at Sanquin Amsterdam.
Title: Hiking the cascade: The Factor XI trail
Host: Matti Pronker
Blood coagulation is orchestrated by regulated assembly of protein complexes that maintain hemostatic balance. Factor XI (FXI) plays a central yet incompletely understood role in the intrinsic pathway, linking clot stabilization and inflammatory signaling. Growing interest in FXI as an antithrombotic target highlights the need for mechanistic understanding. Bassem’s work defines the structural basis of protein complexes using cryo–electron microscopy.
Bassem is an Assistant Professor of Biochemistry and Molecular Biology at Saint Louis University School of Medicine. He earned his PhD at Virginia Commonwealth University and completed postdoctoral training at Vanderbilt and Washington University in St. Louis, focusing on Factor XI, contact activation, and immune responses. His laboratory studies the structural and functional regulation of intrinsic pathway coagulation proteins.