Thesis Tom Arfman

On 29 October 2025 (4:00 PM) Sanquin researcher Tom Arfman expects to defend his PhD thesis 'PAD4 takes charge: Detection and quantification of protein citrullination ' at the University of Amsterdam. 

Promotor: Prof JJ Voorberg PhD
Copromotor:  GAF Nicolaes PhD

Venue: Agnietenkapel, University of Amsterdam

Cover thesis Tom Arfman

Abstract

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Chapters


Chapter 1

General introduction and scope of this thesis

Chapter 2

PAD4 takes charge during neutrophil activation: impact of PAD4 mediated NET formation on immune-mediated disease abstract

Chapter 3

Elevated levels of citr ullinated fibrinogen in patients with cancer abstract

Chapter 4

Pho-PG, an IMAC-enrichable citrullination probe

Chapter 5

Monitoring protein citrullination using targeted mass spectrometry

Chapter 6

ADAMTS13 uncharged: PAD4-mediated citrullination of ADAMTS13

Chapter 7

Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity abstract

Chapter 8

General discussion

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