Thesis Merel Wemelsfelder

On 20 May 2025 (4:00 PM) Sanquin researcher Merel Wemelsfelder defended her PhD thesis 'Optimizing the blood supply chain: A data-driven approach to improve blood product utilization and patient safety' at the University of Amsterdam

Promotor: Prof D den Hertog PhD
Copromotor: MP Janssen PhD
Venue: Agnietenkapel, University of Amsterdam

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Chapters

Chapter 1
Introduction

Part I Reducing alloimmunization risks through extended red blood cell matching
Chapter 2
Introducing a new model for matching extensively typed red blood cells

Chapter 3
Considering patiƫnt alloimmunization risk for extensive matching

Chapter 4
Optimizing matching policies to reduce long-term immune responses

Chapter 5
Investigating the use of Deep Q-learning to find optimal matching policies

Part II Improving efficiency by optimizing parts of the supply chain
Chapter 6
Determining optimal locations for blood distribution centers

Chapter 7
Developing a robust autonomous method for blood demand forecasting

Chapter 8
Using deep reinforcement learning to find platelet inventory-allocation policies

Chapter 9
Disscussion

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