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Thijs (TJW) van de Laar PhD

Blood-borne infections

Medicinal chemistry and Environmental sciences (major molecular toxicology), Vrije Universiteit, Amsterdam


Molecular Epidemiology of Hepatitis C Virus
2007 - University of Amsterdam

Research interests
Molecular Biology and Epidemiology, Virus Diagnostics, Blood-borne and Sexually Transmitted Infections

Conventional, Serological and Molecular detection of infectious agents, Optical Mapping Cloning and various other molecular biological techniques

2013-present Post-doc at the Dept of Blood-borne Infections, Sanquin, Amsterdam
Staff at Dept of Viral Nucleic Acid Diagnostic Services, Sanquin, Amsterdam
2012-2013 Medical Molecular Microbiologist; Staff at Dept of Medical Microbiology & Infection Control, VU medical centre, Amsterdam
2010-2012 Traineeship: Medical Molecular Microbiologist (MMM)
Dept. Medical Microbiology & Infection Control, VU medical centre, Amsterdam.
Supervision: Prof HM Savelkoul PhD
2008-2010 Post-doc at Laboratory of Public Health, Health Service Amsterdam
2003-2007 PhD student at Laboratory of Public Health, Health Service Amsterdam, Faculty of Medicine, University of Amsterdam
Promotor: Prof RA Coutinho PhD
Sanquin publications
Other publications

Markov P, Van de Laar T,Thomas X, Aronson S, van den Berk G, Weegink C, Prins M, Pybus O, Schinkel J. Colonial history and contemporary transmission shape the genetic diversity of hepatitis C genotype 2 in Amsterdam. J Virol 2012; 86(14): 7677-87

Vriend H, Op de Coul E, van de Laar T, Urbanus A, van der Klis F, Boot H. Hepatitis C seroprevalence in the Netherlands. Eur J Public Health 2012; 22(6):819-21.

Rhagwani J, Thomas X, Koekkoek S, Schinkel J, Molenkamp R, van de Laar T, Takebe Y, Tanaka Y, Mikozami M, Rambaut A, Pybus O. Origin and evolution of the unique hepatitis C virus circulating recombinant form 2k/1b. J Virol 2012; 86(4):2212-20.

van den Berg C, Grady B, Schinkel J, van de Laar T, Molenkamp R, van Houdt R, Coutinho R, van Baarle D, Prins M. Female sex and IL28B, a synergism for spontaneous viral clearance in hepatitis C seroconverters from a community-based cohort. PLoS One 2011; 6(11):e27555

Urbanus A, van de Laar T, Van den Hoek A, Zuure F, Speksnijder A, Baaten G, Heijman T, Vriend H, Op de Coul E, Coutinho R, Prins M. Hepatitis C in the general population of various ethnic groups living in the Netherlands: should-non-western migrants be screened? J Hepatol 2011; 55(6):1207-14

Van de Laar T. Acute hepatitis C virusinfectie bij hiv-positieve mannen die seks hebben met mannen: epidemiologie, diagnose en behandeling. Tijdschrift voor Infectieziekten 2011; 6:42-50.

Van de Laar T, Paxton W, Zorgdrager F, Cornelissen M, de Vries H. Sexual transmission of hepatitis C virus in HIV-negative men who have sex with men: a series of case reports. Sex Transm Dis 2011; 38(2):102-4.

Vogel M, van de Laar T, Küpfer B, Stelbrink H, Kümmerle T, Mauss S, Knecht G, Berger A, Bruisten S, Rockstroh J. Phylogenetic analysis of acute hepatitis C genotype 4 infections among HIV-positive men who have sex with men in Germany. Liver Int 2010; 30(8):1169-72.

Van de Laar T, G Matthews, M Prins, M Danta. Acute hepatitis C in HIV-infected men who have sex with men: an emerging sexually transmitted infection. AIDS 2010; 24(12):1799-812

Urbanus A, van Houdt R, van de Laar T, Coutinho R. Viral hepatitis among men who have sex with men, epidemiology and public health consequences. Euro Surveill 2009; 14(47):e19421.

de Bruijne J, Schinkel J, Prins M, Koekkoek S, Aronson S, van Ballegooijen M, Reesink H, Molenkamp R, Van de Laar T. Emergence of hepatitis C virus genotype 4: phylogenetic analysis reveals three distinct epidemiological profiles. J Clin Microbiol 2009; 47(12):3832-8.

Van de Laar T, Molenkamp R, van den Berg C, Schinkel J, Beld M, Prins M, Coutinho R, Bruisten S. Frequent HCV reinfection and superinfection in a cohort of injecting drug users in Amsterdam. J Hepatol 2009; 51(4):667-74.

Urbanus A, van de Laar T, Stolte I, Schinkel J, Heijman, T Coutinho R, Prins M. Hepatitis C virus infections among HIV-infected men who have sex with men: an expanding epidemic. AIDS 2009; 23(12):F1-7.

Van de Laar T, Pybus O, Bruisten S, Brown D, Nelson M, Bhagani S, Vogel M, Baumgarten A, Chaix M, Fisher M, Götz H, Matthews G, Neifer S, White P, Rawlinson W, Pol S, Rockstroh, J Coutinho R, Dore G, Dusheiko G, Danta M. Evidence of a large, international network of HCV transmission in HIV-positive men who have sex with men. Gastroenterology 2009; 136(5):1609-17

van den Berg C, van de Laar T, Kok A, Zuure F, Coutinho R, Prins M. Never injected, but hepatitis C virus-infected: a study among self-declared never-injecting drug users from the Amsterdam cohort studies. J Viral Hepat 2009; 16(8):568-77

Ruys T, Nanlohy N, van den Berg C, Hassink E, Beld M, van de Laar T, Bruisten S, Wit F, Krol A, Prins M, Lange J, van Baarle D. HCV-specific T-cell responses in injecting drug users: evidence for previous exposure to HCV and a role for CD4+ T cells focusing on nonstructural proteins in viral clearance. J Viral Hepat 2008; 15(6):409-20.

Van de Laar T, van der Bij A, Prins M, Bruisten S, Brinkman K, Ruys T, van der Meer J,de Vries H, Mulder J, van Agtmael M, Jurriaans S, Wolthers, Coutinho R. Increase in HCV-incidence among men who have sex with men in Amsterdam most li K kely caused by sexual transmission. J Infect Dis 2007; 196(2):230-8.

Van de Laar T, Koppelman M, van der Bij A, Zaaijer H, Cuijpers H, van der Poel C, Coutinho R, Bruisten S. Diversity and origin of hepatitis C virus infection among unpaid blood donors in the Netherlands. Transfusion 2006; 46(10):1719-28.

Van de Laar T, Langendam M, Bruisten S, Welp E, Verhaest I, van Ameijden E, Coutinho R, Prins M. Changes in risk behaviour and dynamics among young drug users in Amsterdam, the Netherlands. J Med Virol 2005; 77(4):509-18.

Last edited on: 21 July 2016
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