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Marlieke (MLM) Jongsma PhD


Biomedical Sciences

Research interests

Intracellular trafficking of MHC class I and MHC class II molecules

  • Flow Cytometry
  • Cell culture
  • Western Blotting
  • qPCR
  • Immuneprecipitation
  • Confocal microscopy
  • RNA interference
  • Cloning
2013-present Sr Technician, Dept of Immunopathology, Sanquin, Amsterdam
2007-2013 PhD student, Dept of Cell Biology II, NKI, Amsterdam
2006-2007  2nd Master Internship, Dept of Tumor Biology, NKI, Amsterdam
2005-2006 1st Master Internship, Dept of Cell Biology, UMCU, Utrecht
2002-2005 Bachelor BioMedical Sciences, University of Utrecht
Sanquin publications
Other publications

Jongsma ML, Neefjes J. Assaying peptide translocation by the peptide transporter TAP. Methods Mol Biol 2013; 960:53-65.

Neefjes J, Jongsma ML, Paul P, Bakke O. Towards a systems understanding of MHC class I and MHC class II antigen presentation (only MHC Class II part). Nat Rev Immunol 2011; 11(12):823-36.

van den Hoorn T*, Paul P*, Jongsma ML*, Neefjes J. Routes to manipulate MHC Class II Antigen Presentation. Curr Opin Immunol 2011; 23(1):88-95.
* Shared First authorship

Paul P*, van den Hoorn T*, Jongsma ML*, Bakker MJ, Hengeveld R, Janssen L, Cresswell P, Egan DA, van Ham M, Ten Brinke A, Ovaa H, Beijersbergen RL, Kuijl C, Neefjes J*. A Genome-wide Multi-Dimensional RNAi Screen Reveals Pathways Controlling MHC Class II Antigen Presentation. Cell 2011; 145(2):268-83

Last edited on: 8 September 2015
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