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Marea (MVE) van der Rijst

Department
Experimental Immunohematology
E-mail
m.vanderrijst@sanquin.nl
Training

BSc Medical Natural Sciences (VU University, Amsterdam), MSc Drug Discovery and Safety (Dept. Chemistry and Pharmaceutical Sciences, VU University Amsterdam)

Research interests
The evolutionarily conserved transmembrane protein SMIM1 (SMall Integral Membrane protein 1) is recently identified as the underlying gene for the VEL blood group. VEL-negative individuals have a homozygous 17bp-deletion in SMIM1. Studies in zebrafish and a GWAS meta-analysis showed that smim1 has a functional important role in red blood cell formation. There is currently no knowledge about the molecular mechanisms through which SMIM1 exerts its function. My project will focus of identifying the role of SMIM1 during erythropoiesis and in erythrocytes.
Technology
  • Flow cytometry
  • Western Blot
  • PCR
  • Lentivirus production
  • Cell Culture
  • Cloning

Resume
2015-present PhD student at the Dept of Immunohematology Experimental, Sanquin Research
2014 Research technician at the Dept of Hematopoiesis, Sanquin Research
2014 Traineeship (MSc) at the Dept of Hematopoiesis, Sanquin Research Amsterdam
2013 Traineeship (MSc) at the Dept of Medicinal Chemistry and Molecular Toxicology, VU University, Amsterdam
2012-2014 MSc degree in Drug Discovery and Safety, Dept of Chemistry and Pharmaceutical Sciences, VU University, Amsterdam
2011 Traineeship (BSc) at the Dept of Medicinal Chemistry, VU University, Amsterdam
2008-2012 BSc degree in Medical Natural Sciences, VU University, Amsterdam
Publications
Sanquin publications
Other publications


 

Last edited on: 21 April 2016
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