Profiles of Transfusion Recipients (PROTON-study)
Information on blood recipients from 1995-2006 was collected in 20 Dutch hospitals to establish the PROTON dataset, containing 2.4 million transfusions and recipients thereof. Data were linked to mortality databases (GBA) and hospital discharge diagnoses databases (LMR) at Statistics Netherlands (CBS). PROTON encompasses 28% of total Dutch blood use. Detailed analysis of clinical subgroups is envisioned for 2011 by a new post-doc position. It is envisioned that after PROTON, updated analyses are needed. In collaboration with Clinical Consultancy Services of Sanquin Blood Bank and the AIM tool developed by America´s Blood Centers, TTA offered for a program of Data ANalysis for ongoing OPtimization of the TRAnsfusion chain DANOPTRA), with the vision to provide an infrastructure for ongoing modeling studies.
The relationship between age and diagnosis of red blood cell recipients.
Key publications
- Janssen MP. Modelling Blood Safety. PhD Thesis October 19, 2010 University Utrecht, ISBN 978-90-393-5401-8.
- Borkent-Raven BA. The PROTON study: Profiles of transfusion recipients in the Netherlands. PhD Thesis November 9, 2010 University Utrecht, ISBN 978-90-393-5407-0.
- Borkent-Raven BA, Janssen MP, van der Poel CL, Schaasberg WP, Bonsel GJ, van Hout BA. Survival after transfusion in the Netherlands. Vox Sang 2011; 100(2):196-203.
- Borkent-Raven BA, Janssen MP, van der Poel CL. Demographic changes and predicting the blood supply and demand in the Netherlands. Transfusion 2010; 50(11):2455-60.
- Borkent-Raven BA, Janssen MP, van der Poel CL, Schaasberg WP, Bonsel WP, and van Hout BA. The PROTON study: profiles of blood product transfusion recipients in the Netherlands. Vox Sang 2010; 99(1):54-64.