Modeling the shelf-life of blood components in relation to adverse outcomes

TTA collaborated with LUMC on observational research based on PROTON data for possible associations of storage time of blood products and the risk of TRALI. Generalized linear models suggest that extended storage of platelets in plasma may be associated with increased TRALI risk. Storage of FFP for 2 years and red blood cells for 35 days was not associated with increased TRALI risk. Further studies of recipient outcomes (mortality) in relation to shelf-life of products are envisioned.